Not a concern, rather more of learning the controls that might need to be put into place if a company requires certification for ISO 90001. Integration, in my opinion, would be eased in by the controls put into place to be compliant.
Depending on the context of the organization, the company will need to define and document specific controls. Also you need to look at the risks related to your products, processes and resources to determine the required controls. Those controls include engineering controls procedures (e.g. procedure for control of non-conforming product), work instructions, plans, etc. You can decide to implement them following a particular hierarchy (e.g. elimination) and also you can consider to use some controls in combination.